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How long does it take for a hCG 10,000 injection to be released? Features of the ovulation stimulation protocol with a hCG injection: indications, procedure algorithm, effectiveness. Contraindications and side effects

Pathologies of the uterus

Almost every woman who plans to get pregnant knows what hCG is. This one is after the egg is fertilized. However, this does not happen with anovulation. That is, problems arise with the further occurrence, maintenance and development of pregnancy.

An injection of hCG to stimulate ovulation is used after the doctor detects a dominant follicle. The injection allows it to grow to the required size and burst.

What is a hormone?

Human chorionic gonadotropin (hCG) is a specific human hormone that contains subunits such as alpha and. The second has no analogues in the body, so pregnancy tests are made on its basis. It is produced in the first weeks of embryo development. Its number is growing significantly. However, from the 11th week, the concentration of the hormone may decrease.

During this period, it is necessary to monitor the peculiarities of the course of pregnancy. Jumps in hCG levels may indicate pathologies of fetal development and the threat of miscarriage. If the amount of the hormone is insufficient, then the woman has an abortion or its onset becomes impossible.

HCG promotes the production of progesterone and estrogen. The formation of the corpus luteum, the proper development and attachment of the embryo to the uterine mucosa depend on these hormones. It is he who ensures the preservation of pregnancy even before the formation of the placenta.

Indications and contraindications for use of the product

HCG drugs have a luteinizing gonadotropic effect. They stimulate the onset of ovulation in women. They should be used if the patient has:

  • dysfunction of the gonads, provoked by improper functioning of the pituitary gland and hypothalamus;
  • anovulatory infertility (that is, lack of formation of a dominant follicle and development of the egg);
  • insufficient functionality of the corpus luteum;
  • recurrent miscarriage;
  • dysmenorrhea.

HCG injections are required for the normal formation of the placenta in a pregnant woman. Without drugs based on gonadotropins, it is impossible to stimulate ovulation and IVF.

But it is not always possible to use hCG-based medicine. Contraindications include:

  • hypersensitivity to the components of the product;
  • early menopause;
  • congenital or postoperative absence of the gonads;
  • neoplasm in the pituitary gland;
  • hormonally active tumors.

You should also not give hCG injections if you have thrombophlebitis, hypothyroidism, adrenal insufficiency, fallopian tube obstruction, ovarian cancer, or during breastfeeding. The medicine should be used very carefully in case of renal failure, bronchial asthma, migraine, pressure surges, cardiac ischemia, and also in adolescence.

Rules of application

Before you begin the procedure for administering hCG, you need to make sure that it is approved. It is important to follow these rules:

  • Check the degree of patency of the fallopian tubes. If there is a problem, then there is no point in carrying out the procedure. Patency can be determined using laparoscopy or other diagnostic methods.
  • Determine hormonal balance. Tests are taken on the 3rd day of the menstrual cycle. Based on the results, the dosage of stimulant medications can be adjusted.
  • Perform an ultrasound. This procedure will have to be carried out many times. It is imperative to determine a woman’s ovarian reserve.
  • Take a spermogram for your partner, as well as test the compatibility of the couple to conceive a child.

HCG injection 5000 units. most often used if a woman does not ovulate for some reason. In most cases, this dose is enough to start the process. It must be done intramuscularly. A woman can give an injection on her own if she knows how to do it. If this is not possible, then it is better to entrust the procedure to a specialist.

If an injection of hCG is to help stimulate ovulation, then it should be done in the abdomen. This method is faster and more convenient. In addition, an injection in the buttock is characterized by the fact that its pain is more pronounced.

The distance from the navel to the injection site is about 2 cm on the left and right sides. Next, you need to pinch the fold of skin and insert the needle into it all the way to the base. It should be short (preferably insulin). The hCG injection site must be disinfected.

In case of stimulation of ovulation, monitoring using ultrasound is indispensable. It is important to monitor the size of the dominant follicle. As soon as they are as acceptable as possible, an hCG injection is immediately given. It is he who starts the ovulation process. Regression of the follicles is prevented, so the development of cysts is prevented.

One injection is enough to stimulate ovulation. The effectiveness of the procedure is checked by ultrasound on the second or third day. It significantly increases the chance of getting pregnant.

Before stimulation, it is necessary to check the woman’s hormonal levels. Sometimes, to restore her menstrual cycle, it is enough for her to undergo a simple course of treatment without the use of hCG.

Features of the stimulation process

Any interference in the natural processes of the female body does not pass without a trace. All procedures with hormones must be carried out with the permission and under the supervision of doctors. Before prescribing an hCG injection, the specialist must find out the following data:

  • dynamics of follicle enlargement;
  • features of endometrial growth.

And he is also obliged to predict when ovulation should occur. In addition to the injection, the patient may be prescribed concomitant medications: Puregon or Clostilbegit. After the injection, ovulation occurs no later than 36 hours. The following drugs are suitable for injection: Pregnil, Chorionic Gonadotropin. The dosage of the drug is prescribed by the doctor. The most commonly used injection of hCG is 10,000 units.

During this period, it is necessary to have regular sexual intercourse with a partner in order to become pregnant. You should have sex every other day. Next, there is additional stimulation of the functionality of the corpus luteum, which initially ensures the success of pregnancy and embryo development.

How to choose the right dosage?

This question should be addressed to a doctor who has examined the patient and is familiar with the instructions for use. You should not use injections on your own. For the first time, 5000 units of hCG are usually prescribed. If this dosage does not give a positive effect, then it can be increased to 10,000 units, but in the next cycle.

If ovulation has occurred, which was confirmed by ultrasound, then the patient is indicated for additional stimulation of the functionality of the corpus luteum. is prescribed on days 3, 6 and 9 after the release of the egg. The dosage in this case is minimal - no more than 5000 units.

In the presence of recurrent miscarriage, the course of treatment using hCG is long - up to 14 weeks. The first dose of the drug is 10,000 units. Further, the rate decreases. A woman receives 2 injections per week, 5000 units each.

Possible side effects

After stimulation has been carried out, it is important to ensure that ovulation occurs. Sometimes the patient may experience ovarian hyperstimulation syndrome. The follicle simply cannot rupture and develops into a cyst. In addition, the administration of hCG can cause other side effects:

  • gastrointestinal disorders (diarrhea, constipation, nausea);
  • thromboembolism (blockage of blood vessels by a detached blood clot);
  • hydrothorax (accumulation of fluid in the pleural cavity, which is non-infectious);
  • gynecomastia (this symptom is typical for men and manifests itself in enlarged mammary glands);
  • increased sensitivity of the nipples.

The patient may also experience pain and a rash in the area of ​​hCG injection. There is also discomfort in the mammary glands and fever. However, after the stimulation stops, all unpleasant sensations disappear.

Overdose and special instructions for the use of hCG

An overdose of hCG can be accompanied by ovarian hyperstimulation syndrome, which negatively affects a woman’s overall health. That is, the patient develops an excessive number of follicles, which over time degenerate into cysts. Treatment of all side effects is symptomatic.

It is important to remember that long-term use of hCG-based drugs is fraught with the formation. The likelihood of multiple embryos increases (development of multiple pregnancy). During treatment, as well as for a week after its completion, pregnancy tests may show an erroneous result.

If there have already been several unsuccessful attempts at stimulation, in which the dosage of the drugs used was gradually increased, then it is necessary to stop the process and undergo additional tests. After this, treatment methods are reviewed.

If the drug Clostilbegit is used for stimulation, it is recommended to use it no more than 5-6 times throughout life. Otherwise, ovarian wasting syndrome will occur and the woman will not be able to use her own eggs even for artificial insemination.

If stimulation does not give the expected result and pregnancy does not occur, do not give up. Perhaps the long-awaited conception will occur naturally after 2-3 months. Moreover, now there are new reproductive technologies that allow a woman to become a mother.

Human chorionic gonadotropin is a hormone necessary for the fertilization of an egg and maintenance. Sometimes a woman's body produces too little hCG, which prevents her from becoming pregnant. Then synthetic analogues of the hormone are used in the form of an injection.

HCG preparations are made from proteins in the urine of pregnant women. The hormone stimulates the synthesis of progesterone and estrogen - the main hormones that help form the corpus luteum and attach the embryo to the wall of the uterus, and then preserve the fetus until the placenta forms.

The drugs are available in the form of an injection solution and have the following names: Pregnil, Menogon, Novarel. The injection is given in the abdominal area with a syringe with a short insulin needle.

HCG injections stimulate the ovulatory process and are used for the following pathologies:

  • Impaired ovarian function resulting from a malfunction of the hypothalamus and pituitary gland.
  • Dysmenorrhea (menstruation accompanied by severe dizziness and weakness).
  • Infertility, which is anovulatory in nature. That is, there is no dominant one.
  • Insufficient level of functioning of the corpus luteum.
  • Miscarriage (constant miscarriages or frozen pregnancies).
  • Preparation for in vitro fertilization.
  • Maintaining pregnancy.

There are contraindications for the use of such stimulation:

  • Various tumors, cysts in the ovaries.
  • Early menopause.
  • Lactation.
  • Obstruction of the fallopian tubes.
  • Diseases of the adrenal glands.
  • Tendency to thrombosis.
  • Individual intolerance.

Important! For patients with heart and kidney failure, hormones are prescribed only after a thorough examination!

HCG injection 10000 for stimulation

If a woman has impaired egg maturation functions, ovulation does not occur. The reasons for this are: polycystic disease, tumors, prolonged stress. The following situations are usually observed:

  • The follicles do not mature at all.
  • The follicles do not mature completely.
  • The follicle matures, but the egg does not leave the corpus luteum.

The hCG injection is designed to help the formation of the follicle and stimulate the release of the egg.

Before using the hormone, a woman undergoes examination:

  • Tests for hormone levels.
  • Pipe patency examinations.

The hormone is administered when the doctor has determined the development of a dominant follicle on an ultrasound scan at a dosage of 1500-5000 units to stimulate its growth. To stimulate super ovulation in preparation for IVF, hCG is administered once in a dose of 10,000 units.

Ovulation should occur 24-36 hours after the injection. The process is monitored using ultrasound. If ovulation does not occur, then the amount is increased in the next cycle. The exact dosage is determined by the doctor for each specific case.

Important! Self-prescription of hormone therapy is prohibited, as this can lead to serious health consequences.

During ovulation

After the follicle bursts and the egg is released, to further maintain its vital activity and ability to fertilize, the doctor prescribes hCG injections.

Injections are given on days 3, 6 and 9 after ovulation at a dosage of 5000 units. This is necessary to maintain the corpus luteum and help implant the embryo.

During pregnancy

When pregnancy occurs, hCG is administered to prevent miscarriage or miscarriage.

Indications for this are:

  • Risk of miscarriage.
  • A sharp drop in hormone levels.

The hCG level is checked over time, since low levels may occur in the early stages, then they increase.

Important! Before the injection, it is necessary to perform an ultrasound to exclude ectopic pregnancy.

If the pregnancy is intrauterine, then to preserve it, 10,000 units of the drug are first administered, then 5,000 units twice a week. Treatment can last from 8 to 14 weeks, depending on the patient’s condition and hormonal levels. At the same time, Duphaston is prescribed to maintain progesterone levels.

How long will it take to ovulate?

Usually occurs 24-36 hours after administration of the hormone. During this time, for pregnancy to occur, sexual intercourse must occur every day.

Ovulation does not always occur after the injection; sometimes the corpus luteum continues to grow and turns into a cyst. Also, stimulation does not guarantee the onset of your own ovulation in the following months.

Thus, the hCG injection is a one-time stimulation procedure, and not a treatment for infertility.

When to take the test

The level of the hormone increases already on the first day after the injection, so it makes no sense to carry out ovulation tests within three days, as they will be false positive.

You need to check the onset of ovulation 3 days after the procedure.

When to test your hCG level

When pregnancy occurs, hCG levels begin to rise. A strong decrease (20%) indicates serious problems:

  • Risk of miscarriage.
  • Ectopic pregnancy.
  • Delayed fetal development.
  • Placental insufficiency.

To identify these pathologies, an ultrasound scan is necessary before starting hormonal treatment.

Normally, the hormone level constantly increases until the 11th week, then gradually decreases and remains unchanged throughout the entire period of gestation. For an accurate diagnosis, it is necessary to take repeated tests in the same laboratory.

HCG norms in honey/ml:

  • Non-pregnant - 0-5.
  • 1-2 weeks - 25-155.
  • 3-4 weeks - 150-4800.
  • 4-5 weeks - 2500-82000.
  • 5-6 weeks - 23000-150000.
  • 6-7 weeks - 30000-230000.
  • Week 7-10 - 21000-290000.
  • 11-14 weeks - 6000-100000.
  • 16-21 weeks - 4000-80000.
  • 21-39 weeks - 2700-76000.

The first increase is recorded after 11 days of conception, the level doubles every 48 hours. At the level of 1000 units, the fertilized egg is visualized during ultrasound. To confirm the normal course of pregnancy, tests are performed every two days. Indicators may be above normal if:

  • Multiple pregnancy.
  • Gestose.
  • Diabetes mellitus.
  • Down syndrome.

This may also indicate an incorrect determination of the gestational age.

Before donating blood for the hormone, you must meet certain conditions:

  • Take the test at the same time.
  • Do not drink alcohol or smoke.
  • Stop taking medications.
  • Avoid physical activity.
  • For several hours you should not take food or liquids other than water.

Possible complications

A hormone injection is an intervention in the natural processes of the body. Therefore, the following side effects often occur:

  • Ovarian cyst.
  • Vein thrombosis.
  • Ascites (accumulation of fluid in the abdominal cavity).
  • Hyperstimulation syndrome, which causes breathing problems, palpitations, abdominal pain, and dropsy.

Individual reactions may also occur in the form of nausea, vomiting, indigestion, pain in the lower abdomen and lower back, mood swings, and depression. These symptoms disappear after treatment ends.

Important! Hyperstimulation syndrome requires urgent medical attention and is treated in a hospital.

An HCG injection is a necessary support for ovulation and subsequent pregnancy. It is prescribed if a woman does not produce the hormone in sufficient quantities for some reason.

The dosage and regimen of use are chosen by the doctor, depending on the goals and health status of the woman. Typically, pregnancy after such stimulation occurs in the first two months. It should be remembered that the hCG injection is not a means of treating infertility, but a one-time stimulation.

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The level of the pregnancy hormone produced by the placenta (hCG - human chorionic gonadotropin) increases in the female body every day from the moment of fertilization. Thanks to modern medicine, this hormone is created artificially to help treat anovulation in women (a disorder of the menstrual cycle, as a result of which the long-awaited conception does not occur). What is a hCG injection, and in what cases is this method of treatment used? When to do tests after an hCG injection? How many days does it take for the hCG 10,000 injection to be completely eliminated from the body?

Why is an injection of hCG 10,000 prescribed?

With regular absence of ovulation A woman who seeks medical help is often recommended to do so. A few days after stimulation, the first procedure is prescribed Ultrasound , after which this examination is repeated every few days to monitor follicle growth to the required dimensions (twenty to twenty-five mm). Once the required follicle size is reached, an hCG injection is prescribed.

  • The hormone “triggers” ovulation.
  • Prevents follicle regression that can develop into follicular cysts.

Injection dose taken - from 5000 to 10000 units . Ovulation usually happens one day after the injection .

HCG and its effect on pregnancy

The production of the hCG hormone begins from the moment the embryo is implanted in the uterus and continues for all nine months. Based on the presence of the hormone in the female body, we can say about pregnancy . Further, based on its quantitative content, possible violations of the ongoing pregnancy are judged. Thanks to hCG test , you can confirm the fact of pregnancy as early as possible (already on the sixth day after fertilization). This is the most reliable and early method of determining pregnancy, in comparison with traditional test strips. The main function of hCG is to maintain pregnancy and control (in the first trimester) over the production of estrogen and progesterone. Stopping the synthesis of hCG leads to disruption of the production of substances necessary for the fetus. In these cases, the hCG deficiency is replenished artificially, through intramuscular injection. These hCG injections are prescribed in the following cases:

  • For nutrition and maintaining the viability of the corpus luteum until the placenta begins to independently produce the hormones necessary for a successful pregnancy.
  • To form the placenta itself .
  • To stimulate ovulation and supporting the viability of the corpus luteum during pregnancy planning.
  • To prepare for .

Indications for hCG injection

Contraindications for hCG injection

When is an HCG injection given?

When to do ovulation tests after an hCG injection?

The onset of ovulation after an hCG injection occurs within a day (maximum thirty-six hours), after which additional support for the ovaries is prescribed with the help progesterone or utrogestan . Based on the male factor, the timing and frequency of sexual intercourse are assigned individually. If the spermogram is normal - one day (every day) after the hCG injection and until the formation of the corpus luteum. When to do tests?

  • The day of testing depends on the cycle. As you know, the first day of the cycle is the first day of menstruation, and its length is the number of days from the first day of menstruation until the first (inclusive) day of the next one. With a regular cycle, tests begin seventeen days before the start of the next menstruation (after ovulation, the corpus luteum phase lasts about two weeks). For example, with a cycle length of twenty-eight days, testing is carried out starting from the eleventh day.
  • For different cycle durations, select the shortest cycle in six months. Its duration is used to determine the testing day.
  • If there are delays of more than a month, and the cycles are not at all constant, then it is irrational to use tests (given their high cost) without control over follicles and ovulation.
  • Preferably start applying tests daily immediately after diagnosis by ultrasound, achieving the desired follicle size (twenty mm).


It should be remembered that ovulation tests are not informative immediately after hCG injections due to the possible influence of TSH, FSH hormones and dietary habits on the results. Therefore, you should not rely only on tests. It is preferable to use more reliable diagnostic methods (for example, ultrasound ).

When to take pregnancy tests after an hCG injection?

How many days does it take for the hCG 10,000 injection to be completely eliminated from the body? This question worries many. For ten to twelve days after ovulation, those used after an hCG injection may produce false positive results. Accordingly, it is necessary wait one or two weeks . Second option - take a blood test for the hCG hormone in dynamics . The doctor who prescribes treatment and performs stimulation must determine the exact time at which the use of tests can be started.

The level of the pregnancy hormone produced by the placenta (hCG - human chorionic gonadotropin) increases in the female body every day from the moment of fertilization. Thanks to modern medicine, this hormone is created artificially to help treat anovulation in women (a disorder of the menstrual cycle, as a result of which the long-awaited conception does not occur). What is a hCG injection, and in what cases is this method of treatment used? When to do tests after an hCG injection? How many days does it take for the hCG 10,000 injection to be completely eliminated from the body?

With regular absence of ovulation When a woman seeks medical help, she is often advised to stimulation of ovulation . A few days after stimulation, the first procedure is prescribed Ultrasound , after which this examination is repeated every few days to monitor follicle growth to the required dimensions (twenty to twenty-five mm). Once the required follicle size is reached, an hCG injection is prescribed.

  • The hormone “triggers” ovulation.
  • Prevents follicle regression that can develop into follicular cysts.

Injection dose taken - from 5000 to 10000 units . Ovulation usually happens one day after the injection .

The production of the hCG hormone begins from the moment the embryo is implanted in the uterus and continues for all nine months. Based on the presence of the hormone in the female body, we can say about pregnancy . Further, based on its quantitative content, possible violations of the ongoing pregnancy are judged. Thanks to hCG test , you can confirm the fact of pregnancy as early as possible (already on the sixth day after fertilization). This is the most reliable and early method of determining pregnancy, in comparison with traditional test strips. The main function of hCG is to maintain pregnancy and control (in the first trimester) over the production of estrogen and progesterone. Stopping the synthesis of hCG leads to disruption of the production of substances necessary for the fetus. In these cases, the hCG deficiency is replenished artificially, through intramuscular injection. These hCG injections are prescribed in the following cases:

  • For nutrition and maintaining the viability of the corpus luteum until the placenta begins to independently produce the hormones necessary for a successful pregnancy.
  • To form the placenta itself .
  • To stimulate ovulation and supporting the viability of the corpus luteum during pregnancy planning.
  • To prepare for IVF .

The onset of ovulation after an hCG injection occurs within a day (maximum thirty-six hours), after which additional support for the ovaries is prescribed with the help progesterone or utrogestan . Based on the male factor, the timing and frequency of sexual intercourse are assigned individually. If the spermogram is normal - one day (every day) after the hCG injection and until the formation of the corpus luteum. When to do tests?

  • The day of testing depends on the cycle. As you know, the first day of the cycle is the first day of menstruation, and its length is the number of days from the first day of menstruation until the first (inclusive) day of the next one. With a regular cycle, tests begin seventeen days before the start of the next menstruation (after ovulation, the corpus luteum phase lasts about two weeks). For example, with a cycle length of twenty-eight days, testing is carried out starting from the eleventh day.
  • For different cycle durations, select the shortest cycle in six months. Its duration is used to determine the testing day.
  • If there are delays of more than a month, and the cycles are not at all constant, then it is irrational to use tests (given their high cost) without control over follicles and ovulation.
  • Preferably start applying tests daily immediately after diagnosis by ultrasound, achieving the desired follicle size (twenty mm).

It should be remembered that ovulation tests are not informative immediately after hCG injections due to the possible influence of TSH, FSH hormones and dietary habits on the results. Therefore, you should not rely only on tests. It is preferable to use more reliable diagnostic methods (for example, ultrasound ).

When to take pregnancy tests after an hCG injection?

How many days does it take for the hCG 10,000 injection to be completely eliminated from the body? This question worries many. For ten to twelve days after ovulation, pregnancy tests used after an hCG injection may give false positive results. Accordingly, it is necessary wait one or two weeks . Second option - take a blood test for the hCG hormone in dynamics . The doctor who prescribes treatment and performs stimulation must determine the exact time at which the use of tests can be started.

In modern reproductive medicine, a large number of techniques are practiced that allow a woman to quickly become pregnant and successfully carry a child to term.

Conservative methods include injections of the hCG hormone, which can stimulate ovulation in women of reproductive age.

In the article we will talk in detail about this procedure and how long after it ovulation occurs.

What kind of protocol is this?

Human chorionic gonadotropin is a specific hormone that is produced in the female body in the first weeks after pregnancy. It helps maintain pregnancy and prepares the endometrium for the implantation of a fertilized egg. Other the function of hCG is to stimulate the production of sex hormones progesterone and estradiol, which in turn ensure timely and complete ovulation.

The protocol for stimulating ovulation with an hCG injection is an individually developed scheme for administering a hormonal drug with constant monitoring of the condition of the ovaries and control of possible side effects.

The main purpose of introducing human chorionic gonadotropin is the formation of complete eggs in the female body, ready for fertilization. It acts specifically on the ovaries, promoting the natural maturation of the egg, its release from the follicle and movement into the fallopian tube. Under ultrasound control, it is possible to accurately create a picture of this physiological process and calculate the most favorable time for conception.

Important! Stimulating ovulation with an hCG injection will only be effective if the doctor accurately determines the cause of infertility.

When should this injection be given?

Injections of human chorionic gonadotropin are performed if the following indications exist:

Preliminary examinations and analyzes

The injection of gonadotropin is preceded by a whole series of studies - both laboratory and instrumental. They help to identify contraindications to the procedure and study the individual characteristics of the patient. It is imperative to consult a therapist, who will comprehensively assess the woman’s health condition. Instrumental studies:

  • Ultrasound of the pelvic organs;
  • hysteroscopy to confirm the patency of the fallopian tubes;
  • electrocardiogram;
  • folliculometry.

Laboratory research:

  • study of sex hormones and thyroid hormones;
  • tests for antibodies to HIV;
  • Wasserman reaction (RW) to the detection of syphilis;
  • bacterial cultures for candidiasis and trichomoniasis;
  • examination of smears from the cervical canal for the degree of purity and atypical cells;
  • studies for TORCH infections (rubella, cytomegalovirus, chlamydia, toxoplasma).

Important! The male partner must take a spermogram to rule out infertility and identify possible diseases of the genital area.

Application of injection

After all the studies have been completed, the patient undergoes a blood test to study the ovarian reserve. This study allows you to assess the chances of a positive outcome of stimulation and select the optimal regimen for administering the hormone. In addition to assessing ovarian reserve, the scheme should take into account the woman’s body weight and the effect of previous stimulations, if any.

Dosage 5000 and 10000 IU

Injections of human chorionic gonadotropin are prescribed in various dosages according to indications, but the following doses are most often used:

  • 5000 IU– prescribed to stimulate ovulation in its absence, as well as to stimulate the development of the corpus luteum;
  • 10000 IU– prescribed for superovulation before artificial insemination.

The date of hormone administration is set only after an ultrasound scan., which will show a dominant follicle measuring about 2 cm. As soon as such a formation is detected, an injection can be given.

Step by step procedure

  1. Prepare a syringe with a thin insulin needle (2 mm), injection powder, an ampoule with saline solution, a cotton swab and alcohol.
  2. Wash your hands thoroughly with soap.
  3. Take an ampoule with saline solution in your hands and shake off drops of liquid from the tip of the ampoule.
  4. Place your thumb on the indication line on the spout and break off the tip. To avoid cutting yourself, you can use a napkin.
  5. Perform the same actions with the ampoule with powder.
  6. Draw saline solution into the syringe, holding the ampoule at an angle.
  7. Slowly add saline solution into the ampoule with the powder; you can shake it slightly so that the powder dissolves faster.
  8. Without removing the needle from the ampoule, draw all the contents into the syringe.
  9. Remove any remaining air from the syringe using the plunger.
  10. Determine the injection area - to do this, step back from the navel to the left or right by 2 cm.
  11. Treat the injection area on the abdomen with a cotton ball soaked in alcohol.
  12. With one hand, grab the fold of skin on the abdomen, and with the other, puncture the entire length of the syringe with a needle. Movements must be sharp and precise.
  13. Inject the entire volume of medication and remove the needle. Press down the puncture site with a cotton swab until the bleeding stops.

Contraindications

Stimulation of ovulation with human chorionic gonadotropin is not carried out in the following cases:

  • the beginning of menopause;
  • obstruction of the fallopian tubes;
  • dysfunction of the thyroid gland;
  • increased tendency to form blood clots;
  • local or general infectious processes;
  • unsatisfactory spermogram results of the partner;
  • neoplasms of the female genital area, including benign and hormone-dependent ones;
  • imbalance of female and male hormones in the patient’s body;
  • congenital or postoperative absence of the gonads;
  • tumors in the pituitary gland;
  • lactation period;
  • allergy to the components of the drug.

The procedure is carried out with caution in case of bronchial asthma, renal failure, coronary heart disease, frequent migraines, hypertension and hypotension.

Important! Stimulation of ovulation with hCG is carried out no more than 6 times, otherwise the risk of malignant tumors increases.

Possible side effects

The hormonal nature of medications to stimulate the ovulatory process leads to the development of side effects. These include:

After cessation of stimulation, unpleasant symptoms disappear, and for most women it does not occur at all.

How many hours after the procedure does the egg release from the follicle?

The effectiveness of the technique depends on several factors:

  • root causes of ovulatory dysfunction;
  • woman's age;
  • type of drug used;
  • the presence of concomitant diseases and factors affecting reproductive function.

Studies show that in 75% of cases, subject to a well-designed protocol, hCG injections ensure effective maturation and release of the egg. In other cases, repeated stimulation is required for another 2-3 cycles.

After the hormone injection, ovulation occurs within the next 25-36 hours. To confirm this, an ultrasound examination is performed, which will show the mature egg. If the study reveals that the mature follicle has not burst, a maintenance injection may be prescribed to resume the ovulatory process.

Important! If after 36 hours the egg has not been released, we can state that the technique is ineffective in this menstrual cycle.

Where and at what price can you buy human chorionic gonadotropin?

Human chorionic gonadotropin is a prescription drug. You can purchase it at any pharmacy, but only with a prescription from your doctor. All injection preparations containing hCG are available in powder form in ampoules or vials and are sold in a set with a sterile solvent (saline).

The medicine is available in several dosages, and the cost directly depends on the concentration of the hormone:

  • HCG 500 IU – about 430 rubles per pack;
  • HCG 1000 IU – about 700 rubles;
  • HCG 1500 IU – 1200 rubles;
  • HCG 5000 IU – 2500 rubles.

Each package contains 5 bottles of the active substance.

Reproduction specialists do not recommend abusing medications containing hCG, since hormones can lead to exhaustion and hyperstimulation of the ovaries. As a result, a large number of follicles are formed that can degenerate into a tumor, and the eggs become unsuitable for fertilization even artificially.

With prolonged use of the hormone, the body produces antibodies to it and becomes immune to the drug. Therefore, if stimulation of ovulation with an hCG injection over several cycles is unsuccessful, the treatment is reviewed and additional diagnostics are carried out.

If ovulation occurs under the influence of an hCG injection, the woman is prescribed additional medications containing progesterone. They will help support ovarian function and promote effective conception.

Advice to the patient:

  • do not self-medicate and strictly follow the dosage prescribed by the doctor;
  • when planning a pregnancy, have sex according to an individual schedule drawn up by a doctor;
  • an ovulation test can be performed 3 days after the stimulation procedure;
  • after a hormone injection, a pregnancy test is carried out no earlier than 2 weeks after ovulation;
  • If you experience persistent side effects after the procedure, you should inform your doctor.

Stimulating ovulation is not a panacea for infertility. The procedure will give a positive result only if the reason for the lack of ovulation is accurately identified and the likely risks for the patient are assessed.